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Gene: Tbc1d5 (TBC1 domain family, member 5) Rattus norvegicus
Symbol: Tbc1d5
Name: TBC1 domain family, member 5
CRRD ID: 1561626
Description: Predicted to have several functions, including AP-2 adaptor complex binding activity; GTPase activator activity; and retromer complex binding activity. Predicted to be involved in several processes, including activation of GTPase activity; positive regulation of receptor internalization; and retrograde transport, endosome to Golgi. Predicted to colocalize with AP-2 adaptor complex and Atg1/ULK1 kinase complex. Orthologous to human TBC1D5 (TBC1 domain family member 5); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,5-hexanedione; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC501088; RGD1561626; similar to TBC1 domain family, member 5; TBC1 domain family member 5
Homo sapiens (human) : TBC1D5 (TBC1 domain family member 5)  HGNC  Alliance
Mus musculus (house mouse) : Tbc1d5 (TBC1 domain family, member 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbc1d5 (TBC1 domain family member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : TBC1D5 (TBC1 domain family member 5)
Canis lupus familiaris (dog) : TBC1D5 (TBC1 domain family member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbc1d5 (TBC1 domain family member 5)
Sus scrofa (pig) : TBC1D5 (TBC1 domain family member 5)
Chlorocebus sabaeus (African green monkey) : TBC1D5 (TBC1 domain family member 5)
Heterocephalus glaber (naked mole-rat) : Tbc1d5 (TBC1 domain family member 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.091,144,641 - 1,747,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl91,145,700 - 1,746,397 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.091,106,437 - 1,325,473 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.091,393,160 - 1,704,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.494,112,690 - 4,650,663 (+)NCBIRGSC3.4rn4RGSC3.4
Celera9417,936 - 917,218 (-)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tbc1d5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1561626
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.