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Gene: Tbc1d5 (TBC1 domain family, member 5) Rattus norvegicus
Symbol: Tbc1d5
Name: TBC1 domain family, member 5
Description: Predicted to have several functions, including AP-2 adaptor complex binding activity; GTPase activator activity; and retromer complex binding activity. Predicted to be involved in several processes, including activation of GTPase activity; positive regulation of receptor internalization; and retrograde transport, endosome to Golgi. Predicted to colocalize with the AP-2 adaptor complex and Atg1/ULK1 kinase complex. Orthologous to human TBC1D5 (TBC1 domain family member 5); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH (RS)-amphetamine; 1,3-dinitrobenzene; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC501088; RGD1561626; similar to TBC1 domain family, member 5; TBC1 domain family member 5
Homo sapiens (human) : TBC1D5 (TBC1 domain family member 5)  HGNC  Alliance
Mus musculus (house mouse) : Tbc1d5 (TBC1 domain family, member 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbc1d5 (TBC1 domain family member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : TBC1D5 (TBC1 domain family member 5)
Canis lupus familiaris (dog) : TBC1D5 (TBC1 domain family member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbc1d5 (TBC1 domain family member 5)
Sus scrofa (pig) : TBC1D5 (TBC1 domain family member 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.091,144,641 - 1,747,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.091,393,160 - 1,704,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.091,106,437 - 1,325,473 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.494,112,690 - 4,650,663 (+)NCBIRGSC3.4rn4RGSC3.4
Celera9417,936 - 917,218 (-)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tbc1d5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1561626
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.