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Gene: Tnik (TRAF2 and NCK interacting kinase) Rattus norvegicus
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Symbol: Tnik
Name: TRAF2 and NCK interacting kinase
Description: Predicted to have protein serine/threonine kinase activity. Involved in positive regulation of dendrite morphogenesis. Localizes to the glutamatergic synapse; postsynaptic density, intracellular component; and presynapse. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TNIK (TRAF2 and NCK interacting kinase); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; INTERACTS WITH (RS)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC294917; RGD1561817; similar to Traf2 and NCK interacting kinase, splice variant 4; TRAF2 and NCK-interacting protein kinase
Orthologs:
Homo sapiens (human) : TNIK (TRAF2 and NCK interacting kinase)  HGNC  Alliance
Mus musculus (house mouse) : Tnik (TRAF2 and NCK interacting kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnik (TRAF2 and NCK interacting kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : TNIK (TRAF2 and NCK interacting kinase)
Canis lupus familiaris (dog) : TNIK (TRAF2 and NCK interacting kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnik (TRAF2 and NCK interacting kinase)
Sus scrofa (pig) : TNIK (TRAF2 and NCK interacting kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02113,984,599 - 114,391,805 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02133,688,695 - 134,091,198 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42115,599,466 - 116,003,005 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2106,374,076 - 106,767,167 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tnik
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1561817
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.