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Gene: Lefty1 (left right determination factor 1) Rattus norvegicus
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Symbol: Lefty1
Name: left right determination factor 1
Description: Predicted to have cytokine activity and nodal binding activity. Predicted to be involved in several processes, including regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; response to retinoic acid; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to localize to extracellular space. Orthologous to several human genes including LEFTY1 (left-right determination factor 1); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH amphetamine; bisphenol A; furan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: left-right determination factor 1; LOC498299; RGD1561867; similar to Stra3 protein
Orthologs:
Homo sapiens (human) : LEFTY1 (left-right determination factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Lefty1 (left right determination factor 1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LEFTY1 (left-right determination factor 1)
Chlorocebus sabaeus (African green monkey) : LEFTY1 (left-right determination factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01399,212,778 - 99,217,786 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,214,389 - 99,217,786 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,212,236 - 104,215,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,664,408 - 96,667,805 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1392,199,283 - 92,202,680 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Lefty1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1561867
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.