Gene: Tafa5 (TAFA chemokine like family member 5) Rattus norvegicus
Analyze
Symbol:
Tafa5
Name:
TAFA chemokine like family member 5
Description:
Predicted to have cytokine activity. Predicted to be involved in signal transduction. Predicted to localize to the extracellular space. Orthologous to human TAFA5 (TAFA chemokine like family member 5); INTERACTS WITH bisphenol A; endosulfan; vinclozolin.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
chemokine-like protein TAFA-5; Fam19a5; family with sequence similarity 19 (chemokine (C-C motif)-like), member A5; family with sequence similarity 19 member A5, C-C motif chemokine like; LOC500915; RGD1562115; similar to TAFA5; Tafa-5
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TAFA5 (TAFA chemokine like family member 5) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Tafa5 (TAFA chemokine like family member 5) HGNC
EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Tafa5 (TAFA chemokine like family member 5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TAFA5 (TAFA chemokine like family member 5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TAFA5 (TAFA chemokine like family member 5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Tafa5 (TAFA chemokine like family member 5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TAFA5 (TAFA chemokine like family member 5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
TAFA5 (TAFA chemokine like family member 5)
Alliance
DIOPT (Ensembl Compara, HGNC, InParanoid, OMA, OrthoFinder, PANTHER)
Mus musculus (house mouse):
Tafa5 (TAFA chemokine like family member 5)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, PANTHER)
Danio rerio (zebrafish):
tafa5b (TAFA chemokine like family member 5b)
Alliance
DIOPT (InParanoid, OMA, OrthoFinder, PANTHER)
Danio rerio (zebrafish):
tafa5a (TAFA chemokine like family member 5a)
Alliance
DIOPT (Ensembl Compara, InParanoid, OrthoFinder, PANTHER)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 7 128,500,009 - 128,728,834 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 7 128,500,011 - 128,728,928 (+) Ensembl Rnor_5.0 7 128,196,289 - 128,420,388 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 7 125,835,416 - 126,056,345 (+) NCBI RGSC3.4 rn4 RGSC3.4 Celera 7 115,110,201 - 115,330,283 (+) NCBI Celera Cytogenetic Map 7 q34 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Gene-Chemical Interaction Annotations
2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1618249 6480464 Tetrachlorodibenzodioxin affects the expression of TAFA5 mRNA CTD PMID:26377647 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:1342880 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TAFA5 mRNA CTD PMID:22079614 aflatoxin B1 increases methylation ISO RGD:1342880 6480464 Aflatoxin B1 results in increased methylation of TAFA5 intron CTD PMID:30157460 aflatoxin B2 increases methylation ISO RGD:1342880 6480464 aflatoxin B2 results in increased methylation of TAFA5 intron CTD PMID:30157460 all-trans-retinoic acid decreases expression ISO RGD:1342880 6480464 Tretinoin results in decreased expression of TAFA5 mRNA CTD PMID:21934132 arsane affects methylation ISO RGD:1342880 6480464 Arsenic affects the methylation of TAFA5 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1342880 6480464 Arsenic affects the methylation of TAFA5 gene CTD PMID:25304211 arsenous acid increases expression ISO RGD:1342880 6480464 Arsenic Trioxide results in increased expression of TAFA5 mRNA CTD PMID:20458559 azathioprine decreases expression ISO RGD:1618249 6480464 Azathioprine results in decreased expression of TAFA5 mRNA CTD PMID:21621594 benzo[a]pyrene decreases expression ISO RGD:1342880 6480464 Benzo(a)pyrene results in decreased expression of TAFA5 mRNA CTD PMID:20106945 , PMID:21632981 benzo[e]pyrene increases methylation ISO RGD:1342880 6480464 benzo(e)pyrene results in increased methylation of TAFA5 intron CTD PMID:30157460 bisphenol A affects expression ISO RGD:1342880 6480464 bisphenol A affects the expression of FAM19A5 mRNA CTD PMID:30903817 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TAFA5 mRNA CTD PMID:25181051 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of TAFA5 gene CTD PMID:28505145 cisplatin decreases expression ISO RGD:1342880 6480464 Cisplatin results in decreased expression of TAFA5 mRNA CTD PMID:27392435 cisplatin multiple interactions ISO RGD:1342880 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of TAFA5 mRNA CTD PMID:27392435 copper(II) sulfate decreases expression ISO RGD:1342880 6480464 Copper Sulfate results in decreased expression of TAFA5 mRNA CTD PMID:19549813 cyclophosphamide increases expression ISO RGD:1618249 6480464 Cyclophosphamide results in increased expression of TAFA5 mRNA CTD PMID:21621594 cyclosporin A decreases expression ISO RGD:1342880 6480464 Cyclosporine results in decreased expression of TAFA5 mRNA CTD PMID:25562108 cyclosporin A increases expression ISO RGD:1618249 6480464 Cyclosporine results in increased expression of TAFA5 mRNA CTD PMID:21621594 cyclosporin A decreases methylation ISO RGD:1342880 6480464 Cyclosporine results in decreased methylation of TAFA5 promoter CTD PMID:27989131 dexamethasone increases expression ISO RGD:1618249 6480464 Dexamethasone results in increased expression of TAFA5 mRNA CTD PMID:21621594 diarsenic trioxide increases expression ISO RGD:1342880 6480464 Arsenic Trioxide results in increased expression of TAFA5 mRNA CTD PMID:20458559 dibutyl phthalate decreases expression ISO RGD:1618249 6480464 Dibutyl Phthalate results in decreased expression of TAFA5 mRNA CTD PMID:21266533 dorsomorphin multiple interactions ISO RGD:1342880 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of TAFA5 mRNA CTD PMID:29391264 methamphetamine decreases expression ISO RGD:1618249 6480464 Methamphetamine results in decreased expression of TAFA5 mRNA CTD PMID:26307267 methapyrilene increases methylation ISO RGD:1342880 6480464 Methapyrilene results in increased methylation of TAFA5 intron CTD PMID:30157460 methotrexate decreases expression ISO RGD:1618249 6480464 Methotrexate results in decreased expression of TAFA5 mRNA CTD PMID:21621594 methylmercury chloride increases expression ISO RGD:1342880 6480464 methylmercuric chloride results in increased expression of TAFA5 mRNA CTD PMID:26272509 methylmercury chloride multiple interactions ISO RGD:1342880 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAFA5 mRNA CTD PMID:27188386 N-methyl-4-phenylpyridinium increases expression ISO RGD:1342880 6480464 1-Methyl-4-phenylpyridinium results in increased expression of TAFA5 mRNA CTD PMID:24810058 nickel atom decreases expression ISO RGD:1342880 6480464 Nickel results in decreased expression of TAFA5 mRNA CTD PMID:25583101 phenylmercury acetate decreases expression ISO RGD:1342880 6480464 Phenylmercuric Acetate results in decreased expression of TAFA5 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1342880 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TAFA5 mRNA CTD PMID:27188386 prednisolone increases expression ISO RGD:1618249 6480464 Prednisolone results in increased expression of TAFA5 mRNA CTD PMID:21621594 quercetin decreases expression ISO RGD:1342880 6480464 Quercetin results in decreased expression of TAFA5 mRNA CTD PMID:21632981 resorcinol increases expression ISO RGD:1342880 6480464 resorcinol results in increased expression of TAFA5 mRNA CTD PMID:22623647 SB 431542 multiple interactions ISO RGD:1342880 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide decreases expression ISO RGD:1342880 6480464 Silicon Dioxide analog results in decreased expression of TAFA5 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO RGD:1342880 6480464 Silicon Dioxide analog results in increased expression of TAFA5 mRNA CTD PMID:23806026 valproic acid increases methylation ISO RGD:1342880 6480464 Valproic Acid results in increased methylation of TAFA5 gene CTD PMID:29154799 valproic acid increases expression ISO RGD:1342880 6480464 Valproic Acid results in increased expression of TAFA5 mRNA CTD PMID:19101580 , PMID:29154799 valproic acid affects expression ISO RGD:1342880 6480464 Valproic Acid affects the expression of TAFA5 mRNA CTD PMID:25979313 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of TAFA5 mRNA CTD PMID:19015723
Gene Ontology Annotations
Biological Process signal transduction IEA GO:0005125 1600115 GO_REF:0000108 GOC GO_REF:0000108 Cellular Component extracellular space IEA UniProtKB-KW:KW-0202 1600115 GO_REF:0000037 UniProt GO_REF:0000037 Molecular Function cytokine activity IEA UniProtKB-KW:KW-0202 1600115 GO_REF:0000037 UniProt GO_REF:0000037
2306821 Bp335 Blood pressure QTL 335 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 7 115922628 145729302 Rat 631687 Hcas1 Hepatocarcinoma susceptibility QTL 1 3.9 0.001 liver integrity trait (VT:0010547) volume of liver occupied by tumorous lesions as percentage of total liver volume (CMO:0001081) 7 100160423 140335001 Rat 2317052 Aia17 Adjuvant induced arthritis QTL 17 2.13 joint integrity trait (VT:0010548) left rear ankle joint diameter (CMO:0002149) 7 91018361 136018361 Rat 731174 Uae23 Urinary albumin excretion QTL 23 2.4 0.0042 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 7 114825174 145729302 Rat 634331 Pia17 Pristane induced arthritis QTL 17 4.7 joint integrity trait (VT:0010548) arthritic paw count (CMO:0001460) 7 81645773 140745067 Rat 7411654 Foco25 Food consumption QTL 25 9.3 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 7 85595369 130595369 Rat 7411607 Foco15 Food consumption QTL 15 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 7 85595369 130595369 Rat 1300112 Bp183 Blood pressure QTL 183 3.51 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 7 121654760 145729302 Rat 1300179 Kidm5 Kidney mass QTL 5 3.51 kidney mass (VT:0002707) left kidney wet weight (CMO:0000083) 7 51251919 145729302 Rat 1331728 Bp214 Blood pressure QTL 214 2.825 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 7 88365265 134673427 Rat 1331731 Bp216 Blood pressure QTL 216 2.851 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 7 111519266 143965591 Rat 1331748 Bp215 Blood pressure QTL 215 4.043 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 7 121986439 143965591 Rat 1331768 Kidm10 Kidney mass QTL 10 4.62096 kidney mass (VT:0002707) left kidney wet weight (CMO:0000083) 7 88365265 133365265 Rat 1357339 Stl14 Serum triglyceride level QTL 14 3.45 0.0001 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 7 122421276 143965415 Rat 1549899 Stresp8 Stress response QTL 8 4.37 0.0008 stress-related behavior trait (VT:0010451) defensive burying duration (CMO:0001961) 7 100192194 145192194 Rat 1558655 Swd4 Spike wave discharge measurement QTL 4 3.68 0.0002 brain electrophysiology trait (VT:0010557) brain spike-and-wave discharge severity grade (CMO:0001988) 7 96630946 141630946 Rat 1358891 Bp265 Blood pressure QTL 265 2.21 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 7 91832949 145158140 Rat 1358914 Bp266 Blood pressure QTL 266 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 7 91832949 145158140 Rat 1582240 Sffal1 Serum free fatty acids level QTL 1 3.4 0.0021 blood free fatty acid amount (VT:0001553) serum free fatty acids level (CMO:0000547) 7 126463649 134098026 Rat 61357 Bp38 Blood pressure QTL 38 1.6 0.052 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 7 48118835 128611831 Rat 70173 Niddm19 Non-insulin dependent diabetes mellitus QTL 19 4.33 0.00005 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 7 71448715 145729302 Rat 71114 Niddm14 Non-insulin dependent diabetes mellitus QTL 14 4.5 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 7 93726906 138726906 Rat 631201 Panci1 Pancreas inflammation QTL 1 0 0.001 pancreas integrity trait (VT:0010560) percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214) 7 126463827 137325116 Rat 2298475 Eau6 Experimental allergic uveoretinitis QTL 6 0.0029 uvea integrity trait (VT:0010551) experimental autoimmune uveitis score (CMO:0001504) 7 93726906 138726906 Rat 2299163 Iddm34 Insulin dependent diabetes mellitus QTL 34 2.71 blood glucose amount (VT:0000188) age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140) 7 100028953 145729302 Rat 731176 Glom5 Glomerulus QTL 5 2.5 0.0035 kidney glomerulus morphology trait (VT:0005325) count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002) 7 106564316 145729302 Rat 631663 Bw6 Body weight QTL 6 3.4 body mass (VT:0001259) body weight (CMO:0000012) 7 120746024 145692398 Rat
Predicted Target Of
Count of predictions: 555 Count of miRNA genes: 257 Interacting mature miRNAs: 317 Transcripts: ENSRNOT00000074625 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
Gene-Chemical Interaction Annotations
