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Gene: Sh2d1a (SH2 domain containing 1A) Rattus norvegicus
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Symbol: Sh2d1a
Name: SH2 domain containing 1A
Description: Predicted to have SH3/SH2 adaptor activity. Predicted to be involved in cell-cell signaling; humoral immune response; and positive regulation of natural killer cell mediated cytotoxicity. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human SH2D1A (SH2 domain containing 1A); PARTICIPATES IN measles pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; valproic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC501502; RGD1562408; SH2 domain protein 1A; SH2 domain-containing protein 1A; similar to SH2 domain protein 1A (Signaling lymphocyte activation molecule-associated protein); similar to SH2 domain protein 1A (Signaling lymphocyte activation molecule-associated protein) (SLAM-associated protein) (T c ell signal transduction molecule SAP)
Orthologs:
Homo sapiens (human) : SH2D1A (SH2 domain containing 1A)  HGNC  Alliance
Mus musculus (house mouse) : Sh2d1a (SH2 domain containing 1A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh2d1a (SH2 domain containing 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : SH2D1A (SH2 domain containing 1A)
Canis lupus familiaris (dog) : SH2D1A (SH2 domain containing 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh2d1a (SH2 domain containing 1A)
Sus scrofa (pig) : SH2D1A (SH2 domain containing 1A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X128,897,053 - 128,925,408 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX128,897,181 - 128,925,407 (+)Ensembl
Rnor_5.0X128,978,818 - 129,007,045 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X2,532,295 - 2,560,524 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX120,486,695 - 120,514,918 (+)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sh2d1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562408
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.