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Gene: Irs4 (insulin receptor substrate 4) Rattus norvegicus
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Symbol: Irs4
Name: insulin receptor substrate 4
CRRD ID: 1562442
Description: Exhibits protein domain specific binding activity. Localizes to protein-containing complex. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 9. Orthologous to human IRS4 (insulin receptor substrate 4); PARTICIPATES IN insulin signaling pathway; aldosterone signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH acrylamide; bisphenol A; cobalt atom.
Type: protein-coding
RefSeq Status: MODEL
Also known as: IRS-4; LOW QUALITY PROTEIN: insulin receptor substrate 4
Orthologs:
Homo sapiens (human) : IRS4 (insulin receptor substrate 4)  HGNC  Alliance
Mus musculus (house mouse) : Irs4 (insulin receptor substrate 4)  MGI  Alliance
Sus scrofa (pig) : IRS4 (insulin receptor substrate 4)
Chlorocebus sabaeus (African green monkey) : IRS4 (insulin receptor substrate 4)
Heterocephalus glaber (naked mole-rat) : Irs4 (insulin receptor substrate 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X113,003,824 - 113,018,088 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X111,457,261 - 111,471,505 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X36,881,414 - 36,885,105 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX104,754,830 - 104,768,446 (-)NCBICelera
Cytogenetic MapXq33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Irs4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562442
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.