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Gene: Lage3 (L antigen family, member 3) Rattus norvegicus
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Symbol: Lage3
Name: L antigen family, member 3
Description: Predicted to be involved in positive regulation of transcription by RNA polymerase II and tRNA threonylcarbamoyladenosine metabolic process. Predicted to localize to the EKC/KEOPS complex; cytoplasm; and nuclear body. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 2. Orthologous to human LAGE3 (L antigen family member 3); INTERACTS WITH (+)-schisandrin B; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: EKC/KEOPS complex subunit LAGE3; L antigen family member 3; LOC293863; RGD1562476; similar to Eso3 protein
Orthologs:
Homo sapiens (human) : LAGE3 (L antigen family member 3)  HGNC  Alliance
Mus musculus (house mouse) : Lage3 (L antigen family, member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lage3 (L antigen family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LAGE3 (L antigen family member 3)
Canis lupus familiaris (dog) : LAGE3 (L antigen family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lage3 (L antigen family member 3)
Sus scrofa (pig) : LOC100515685 (EKC/KEOPS complex subunit LAGE3 pseudogene)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X156,355,376 - 156,356,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,095,511 - 152,096,934 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,253,757 - 160,255,180 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1135,757,019 - 135,758,442 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lage3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562476
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.