Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pml (promyelocytic leukemia) Rattus norvegicus
Analyze
Symbol: Pml
Name: promyelocytic leukemia
Description: Predicted to have several functions, including protein dimerization activity; transition metal ion binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of cellular protein metabolic process; and regulation of nucleobase-containing compound metabolic process. Predicted to colocalize with heterochromatin. Orthologous to human PML (promyelocytic leukemia); PARTICIPATES IN mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; acute myeloid leukemia pathway; INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315713; RGD1562602; similar to promyelocytic leukemia
Orthologs:
Homo sapiens (human) : PML (PML nuclear body scaffold)  HGNC  Alliance
Mus musculus (house mouse) : Pml (promyelocytic leukemia)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pml (PML nuclear body scaffold)
Pan paniscus (bonobo/pygmy chimpanzee) : PML (PML nuclear body scaffold)
Canis lupus familiaris (dog) : PML (PML nuclear body scaffold)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pml (PML nuclear body scaffold)
Sus scrofa (pig) : PML (PML nuclear body scaffold)
Chlorocebus sabaeus (African green monkey) : PML (PML nuclear body scaffold)
Heterocephalus glaber (naked mole-rat) : Pml (PML nuclear body scaffold)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0863,002,515 - 63,034,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl863,004,870 - 63,034,226 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,778,563 - 62,810,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4862,020,438 - 62,051,927 (-)NCBIRGSC3.4rn4RGSC3.4
Celera858,089,954 - 58,121,691 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pml
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562602
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.