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Gene: Mafa (MAF bZIP transcription factor A) Rattus norvegicus
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Symbol: Mafa
Name: MAF bZIP transcription factor A
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in several processes, including insulin secretion; nitric oxide mediated signal transduction; and response to glucose. Localizes to the nucleus. Biomarker of diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAFA (MAF bZIP transcription factor A); PARTICIPATES IN maturity-onset diabetes of the young pathway; type 2 diabetes mellitus pathway; INTERACTS WITH 3-aminobenzamide; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; acrylamide.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC366949; RGD1562627; similar to pancreatic beta-cell specific transcriptional activator; transcription factor MafA; v-maf avian musculoaponeurotic fibrosarcoma oncogene A; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog A; v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
Orthologs:
Homo sapiens (human) : MAFA (MAF bZIP transcription factor A)  HGNC  Alliance
Mus musculus (house mouse) : Mafa (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mafa (MAF bZIP transcription factor A)
Canis lupus familiaris (dog) : MAFA (MAF bZIP transcription factor A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mafa (MAF bZIP transcription factor A)
Sus scrofa (pig) : MAFA (MAF bZIP transcription factor A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07116,779,368 - 116,781,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07116,670,579 - 116,673,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,707,043 - 113,708,128 (-)NCBIRGSC3.4rn4RGSC3.4
Celera7103,795,440 - 103,796,236 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mafa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562627
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.