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Gene: Arx (aristaless related homeobox) Rattus norvegicus
Symbol: Arx
Name: aristaless related homeobox
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in brain development and neuron development. Localizes to nucleus. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Partington syndrome; early infantile epileptic encephalopathy 1; lissencephaly; non-syndromic X-linked intellectual disability; and syndromic X-linked intellectual disability Hedera type. Orthologous to human ARX (aristaless related homeobox); INTERACTS WITH 6-propyl-2-thiouracil; dibutyl phthalate; gentamycin.
Type: protein-coding
Also known as: aristaless related homeobox gene (Drosophila); aristaless-related homeobox; homeobox protein ARX; LOC317268; RGD1562672; similar to Arx homeoprotein
Homo sapiens (human) : ARX (aristaless related homeobox)  HGNC  Alliance
Mus musculus (house mouse) : Arx (aristaless related homeobox)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arx (aristaless related homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : ARX (aristaless related homeobox)
Canis lupus familiaris (dog) : ARX (aristaless related homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arx (aristaless related homeobox)
Sus scrofa (pig) : ARX (aristaless related homeobox)
Chlorocebus sabaeus (African green monkey) : ARX (aristaless related homeobox)
Heterocephalus glaber (naked mole-rat) : Arx (aristaless related homeobox)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X62,363,757 - 62,376,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX62,363,757 - 62,376,143 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X62,957,562 - 62,969,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X80,631,375 - 80,643,989 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX58,455,664 - 58,467,636 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Arx
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562672
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.