Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Icoslg (inducible T-cell co-stimulator ligand) Rattus norvegicus
Symbol: Icoslg
Name: inducible T-cell co-stimulator ligand
Description: Predicted to have identical protein binding activity and signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and positive regulation of interleukin-4 biosynthetic process. Predicted to localize to cytoplasmic ribonucleoprotein granule; external side of plasma membrane; and integral component of plasma membrane. Orthologous to human ICOSLG (inducible T cell costimulator ligand); INTERACTS WITH (+)-schisandrin B; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: MODEL
Also known as: icos ligand; Icosl; LOC499415; RGD1562791; similar to B7-like protein GL50-B
Homo sapiens (human) : ICOSLG (inducible T cell costimulator ligand)  HGNC  Alliance
Mus musculus (house mouse) : Icosl (icos ligand)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Icoslg (inducible T cell costimulator ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : ICOSLG (inducible T cell costimulator ligand)
Canis lupus familiaris (dog) : ICOSLG (inducible T cell costimulator ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icoslg (inducible T cell costimulator ligand)
Sus scrofa (pig) : ICOSLG (inducible T cell costimulator ligand)
Chlorocebus sabaeus (African green monkey) : ICOSLG (inducible T cell costimulator ligand)
Heterocephalus glaber (naked mole-rat) : Icoslg (inducible T cell costimulator ligand)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02011,330,000 - 11,340,307 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2011,329,992 - 11,340,296 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02013,500,200 - 13,510,518 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,930,797 - 10,954,666 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2012,106,187 - 12,116,495 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Icoslg
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562791
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.