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Gene: Sppl3 (signal peptide peptidase like 3) Rattus norvegicus
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Symbol: Sppl3
Name: signal peptide peptidase like 3
Description: Predicted to have aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; positive regulation of calcineurin-NFAT signaling cascade; and proteolysis. Predicted to localize to the cytoplasm and plasma membrane. Orthologous to human SPPL3 (signal peptide peptidase like 3); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,5-hexanedione; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC360822; RGD1562826; signal peptide peptidase 3; signal peptide peptidase-like 3; signal peptide peptidase-like 3, pseudogene 1; similar to Hypothetical protein MGC75937; Sppl3-ps1
Orthologs:
Homo sapiens (human) : SPPL3 (signal peptide peptidase like 3)  HGNC  Alliance
Mus musculus (house mouse) : Sppl3 (signal peptide peptidase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sppl3 (signal peptide peptidase like 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SPPL3 (signal peptide peptidase like 3)
Canis lupus familiaris (dog) : SPPL3 (signal peptide peptidase like 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sppl3 (signal peptide peptidase like 3)
Sus scrofa (pig) : SPPL3 (signal peptide peptidase like 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01247,276,485 - 47,360,552 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01249,071,961 - 49,156,613 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,788,576 - 42,882,650 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1243,134,305 - 43,170,708 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sppl3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562826
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.