Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ikzf1 (IKAROS family zinc finger 1) Rattus norvegicus
Symbol: Ikzf1
Name: IKAROS family zinc finger 1
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including hematopoietic or lymphoid organ development; positive regulation of leukocyte differentiation; and regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear pericentric heterochromatin; nucleoplasm; and protein-DNA complex. Human ortholog(s) of this gene implicated in common variable immunodeficiency and precursor B lymphoblastic lymphoma/leukemia. Orthologous to human IKZF1 (IKAROS family zinc finger 1); INTERACTS WITH (RS)-amphetamine; bisphenol A; clofibrate.
Type: protein-coding
Also known as: DNA-binding protein Ikaros; LOC305501; RGD1562979; similar to DNA-binding protein Ikaros form 1 - mouse
Homo sapiens (human) : IKZF1 (IKAROS family zinc finger 1)  HGNC  Alliance
Mus musculus (house mouse) : Ikzf1 (IKAROS family zinc finger 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ikzf1 (IKAROS family zinc finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IKZF1 (IKAROS family zinc finger 1)
Canis lupus familiaris (dog) : IKZF1 (IKAROS family zinc finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ikzf1 (IKAROS family zinc finger 1)
Sus scrofa (pig) : IKZF1 (IKAROS family zinc finger 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01491,782,281 - 91,867,828 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01491,567,474 - 91,652,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41492,560,200 - 92,657,336 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1485,257,476 - 85,342,328 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Ikzf1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562979
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.