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Gene: Ikzf1 (IKAROS family zinc finger 1) Rattus norvegicus
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Symbol: Ikzf1
Name: IKAROS family zinc finger 1
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including hematopoietic or lymphoid organ development; positive regulation of leukocyte differentiation; and regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear pericentric heterochromatin; nucleoplasm; and protein-DNA complex. Human ortholog(s) of this gene implicated in common variable immunodeficiency and precursor B lymphoblastic lymphoma/leukemia. Orthologous to human IKZF1 (IKAROS family zinc finger 1); INTERACTS WITH (RS)-amphetamine; bisphenol A; clofibrate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA-binding protein Ikaros; LOC305501; RGD1562979; similar to DNA-binding protein Ikaros form 1 - mouse
Orthologs:
Homo sapiens (human) : IKZF1 (IKAROS family zinc finger 1)  HGNC  Alliance
Mus musculus (house mouse) : Ikzf1 (IKAROS family zinc finger 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ikzf1 (IKAROS family zinc finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IKZF1 (IKAROS family zinc finger 1)
Canis lupus familiaris (dog) : IKZF1 (IKAROS family zinc finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ikzf1 (IKAROS family zinc finger 1)
Sus scrofa (pig) : IKZF1 (IKAROS family zinc finger 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01491,782,281 - 91,867,828 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01491,567,474 - 91,652,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41492,560,200 - 92,657,336 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1485,257,476 - 85,342,328 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ikzf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1562979
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.