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Gene: Tbc1d8b (TBC1 domain family member 8B) Rattus norvegicus
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Symbol: Tbc1d8b
Name: TBC1 domain family member 8B
Description: Predicted to have GTPase activator activity and Rab GTPase binding activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to localize to the cell. Human ortholog(s) of this gene implicated in familial nephrotic syndrome. Orthologous to human TBC1D8B (TBC1 domain family member 8B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; caffeine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315912; RGD1563084; similar to FLJ20298 protein isoform a; TBC1 domain family, member 8B (with GRAM domain)
Orthologs:
Homo sapiens (human) : TBC1D8B (TBC1 domain family member 8B)  HGNC  Alliance
Mus musculus (house mouse) : Tbc1d8b (TBC1 domain family, member 8B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbc1d8b (TBC1 domain family member 8B)
Pan paniscus (bonobo/pygmy chimpanzee) : TBC1D8B (TBC1 domain family member 8B)
Canis lupus familiaris (dog) : TBC1D8B (TBC1 domain family member 8B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbc1d8b (TBC1 domain family member 8B)
Sus scrofa (pig) : TBC1D8B (TBC1 domain family member 8B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X110,894,831 - 110,983,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0353,608,955 - 53,698,013 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X127,388,586 - 127,484,707 (+)NCBIRGSC3.4rn4RGSC3.4
Celera344,520,022 - 44,607,073 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tbc1d8b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563084
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.