Gene: Mef2c (myocyte enhancer factor 2C) Rattus norvegicus
Symbol: Mef2c
Name: myocyte enhancer factor 2C
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific; involved in several processes, including animal organ development, cellular response to glucose stimulus, and cellular response to growth factor stimulus; localizes to the nucleus and sarcomere; used to study myocardial infarction; biomarker of status epilepticus; orthologous to human MEF2C (myocyte enhancer factor 2C); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499497; LOC685671; myocyte-specific enhancer factor 2C; RGD1563119; similar to MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C); similar to myocyte enhancer factor 2C
Homo sapiens (human) : MEF2C (myocyte enhancer factor 2C)  HGNC  Alliance
Mus musculus (house mouse) : Mef2c (myocyte enhancer factor 2C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mef2c (myocyte enhancer factor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : MEF2C (myocyte enhancer factor 2C)
Canis lupus familiaris (dog) : MEF2C (myocyte enhancer factor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mef2c (myocyte enhancer factor 2C)
Sus scrofa (pig) : MEF2C (myocyte enhancer factor 2C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0211,658,534 - 11,822,788 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0211,521,053 - 11,684,949 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4212,331,078 - 12,346,520 (-)NCBIRGSC3.4rn4RGSC3.4
Celera210,288,159 - 10,449,731 (+)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Mef2c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563119
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.