Gene: Mef2c (myocyte enhancer factor 2C) Rattus norvegicus
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Symbol: Mef2c
Name: myocyte enhancer factor 2C
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific; involved in several processes, including animal organ development, cellular response to glucose stimulus, and cellular response to growth factor stimulus; localizes to the nucleus and sarcomere; used to study myocardial infarction; biomarker of status epilepticus; orthologous to human MEF2C (myocyte enhancer factor 2C); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499497; LOC685671; myocyte-specific enhancer factor 2C; RGD1563119; similar to MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C); similar to myocyte enhancer factor 2C
Orthologs:
Homo sapiens (human) : MEF2C (myocyte enhancer factor 2C)  HGNC  Alliance
Mus musculus (house mouse) : Mef2c (myocyte enhancer factor 2C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mef2c (myocyte enhancer factor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : MEF2C (myocyte enhancer factor 2C)
Canis lupus familiaris (dog) : MEF2C (myocyte enhancer factor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mef2c (myocyte enhancer factor 2C)
Sus scrofa (pig) : MEF2C (myocyte enhancer factor 2C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0211,658,534 - 11,822,788 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0211,521,053 - 11,684,949 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4212,331,078 - 12,346,520 (-)NCBIRGSC3.4rn4RGSC3.4
Celera210,288,159 - 10,449,731 (+)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mef2c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563119
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.