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Gene: Dkk4 (dickkopf WNT signaling pathway inhibitor 4) Rattus norvegicus
Symbol: Dkk4
Name: dickkopf WNT signaling pathway inhibitor 4
Description: Predicted to have co-receptor binding activity and receptor antagonist activity. Predicted to be involved in Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; and negative regulation of hair follicle placode formation. Predicted to localize to extracellular space. Orthologous to human DKK4 (dickkopf WNT signaling pathway inhibitor 4); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling pathway; INTERACTS WITH acrylamide; bisphenol A; 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog).
Type: protein-coding
Also known as: dickkopf homolog 4; dickkopf homolog 4 (Xenopus laevis); dickkopf-related protein 4; LOC502097; RGD1563172; similar to Dickkopf homolog 4
Homo sapiens (human) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)  HGNC  Alliance
Mus musculus (house mouse) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Canis lupus familiaris (dog) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)
Sus scrofa (pig) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Chlorocebus sabaeus (African green monkey) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Heterocephalus glaber (naked mole-rat) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01674,260,551 - 74,264,142 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1674,260,551 - 74,264,142 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01673,893,385 - 73,896,976 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,888,290 - 73,891,881 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1667,295,927 - 67,299,518 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dkk4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563172
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.