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Gene: Tigit (T cell immunoreceptor with Ig and ITIM domains) Rattus norvegicus
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Symbol: Tigit
Name: T cell immunoreceptor with Ig and ITIM domains
Description: Predicted to have identical protein binding activity and signaling receptor binding activity. Predicted to be involved in negative regulation of T cell activation; negative regulation of interleukin-12 production; and positive regulation of interleukin-10 production. Predicted to localize to cell surface. Orthologous to human TIGIT (T cell immunoreceptor with Ig and ITIM domains); INTERACTS WITH glyphosate; aflatoxin B1 (ortholog); antirheumatic drug (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC363784; RGD1563191; similar to hypothetical protein; T-cell immunoreceptor with Ig and ITIM domains
Orthologs:
Homo sapiens (human) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)  HGNC  Alliance
Mus musculus (house mouse) : Tigit (T cell immunoreceptor with Ig and ITIM domains)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tigit (T cell immunoreceptor with Ig and ITIM domains)
Pan paniscus (bonobo/pygmy chimpanzee) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Canis lupus familiaris (dog) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tigit (T cell immunoreceptor with Ig and ITIM domains)
Sus scrofa (pig) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Chlorocebus sabaeus (African green monkey) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Heterocephalus glaber (naked mole-rat) : Tigit (T cell immunoreceptor with Ig and ITIM domains)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01161,966,780 - 61,987,749 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1161,970,976 - 61,987,760 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01161,100,049 - 61,120,824 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,618,187 - 58,635,015 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1156,581,374 - 56,598,622 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tigit
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563191
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.