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Gene: Ophn1 (oligophrenin 1) Rattus norvegicus
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Symbol: Ophn1
Name: oligophrenin 1
CRRD ID: 1563435
Description: Exhibits ionotropic glutamate receptor binding activity. Predicted to be involved in several processes, including establishment of epithelial cell apical/basal polarity; negative regulation of proteasomal protein catabolic process; and neuron differentiation. Predicted to localize to several cellular components, including actin cytoskeleton; dendritic spine; and terminal bouton. Human ortholog(s) of this gene implicated in X-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance. Orthologous to human OPHN1 (oligophrenin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hypothetical protein LOC688676; LOC688676; Oligophrenin-1; Opn1
Orthologs:
Homo sapiens (human) : OPHN1 (oligophrenin 1)  HGNC  Alliance
Mus musculus (house mouse) : Ophn1 (oligophrenin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ophn1 (oligophrenin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPHN1 (oligophrenin 1)
Canis lupus familiaris (dog) : OPHN1 (oligophrenin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101977674 (oligophrenin-1)
Sus scrofa (pig) : OPHN1 (oligophrenin 1)
Chlorocebus sabaeus (African green monkey) : OPHN1 (oligophrenin 1)
Heterocephalus glaber (naked mole-rat) : Ophn1 (oligophrenin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X68,185,865 - 68,579,518 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX68,189,161 - 68,563,137 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X69,060,378 - 69,453,851 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X86,519,900 - 86,801,421 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX64,002,740 - 64,359,348 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ophn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563435
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.