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Gene: Man1b1 (mannosidase, alpha, class 1B, member 1) Rattus norvegicus
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Symbol: Man1b1
Name: mannosidase, alpha, class 1B, member 1
Description: Predicted to have mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing; mannose trimming involved in glycoprotein ERAD pathway; and trimming of terminal mannose on B branch. Predicted to localize to endoplasmic reticulum quality control compartment and membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human MAN1B1 (mannosidase alpha class 1B member 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH bisphenol A; C60 fullerene; glafenine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; ER alpha-1,2-mannosidase; ER mannosidase 1; ERMan1; LOC499751; mannosidase alpha class 1B member 1; RGD1563595; similar to Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase); similar to Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific processing alpha-mannosidase) (UNQ747/PRO1477)
Orthologs:
Homo sapiens (human) : MAN1B1 (mannosidase alpha class 1B member 1)  HGNC  Alliance
Mus musculus (house mouse) : Man1b1 (mannosidase, alpha, class 1B, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Man1b1 (mannosidase alpha class 1B member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAN1B1 (mannosidase alpha class 1B member 1)
Canis lupus familiaris (dog) : LOC480667 (endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Man1b1 (mannosidase alpha class 1B member 1)
Sus scrofa (pig) : LOC110258087 (endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase-like)
Chlorocebus sabaeus (African green monkey) : MAN1B1 (mannosidase alpha class 1B member 1)
Heterocephalus glaber (naked mole-rat) : Man1b1 (mannosidase alpha class 1B member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.032,547,259 - 2,569,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,547,986 - 2,569,049 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,528,747 - 2,550,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,493,476 - 3,514,884 (+)NCBIRGSC3.4rn4RGSC3.4
Celera32,970,480 - 2,991,187 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Man1b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563595
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.