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Gene: Scube2 (signal peptide, CUB domain and EGF like domain containing 2) Rattus norvegicus
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Symbol: Scube2
Name: signal peptide, CUB domain and EGF like domain containing 2
Description: Predicted to have hedgehog family protein binding activity. Predicted to be involved in several processes, including positive regulation of chondrocyte proliferation; positive regulation of osteoblast differentiation; and positive regulation of smoothened signaling pathway. Predicted to localize to the cell surface and extracellular space. Orthologous to human SCUBE2 (signal peptide, CUB domain and EGF like domain containing 2); INTERACTS WITH endosulfan; 17alpha-ethynylestradiol (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499241; RGD1563998; Scube2-ps1; signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB domain, EGF-like 2; signal peptide, CUB domain, EGF-like 2, pseudogene 1; similar to Cegp1 protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01174,428,056 - 174,495,356 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01181,412,988 - 181,479,843 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,423,473 - 167,490,273 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1161,729,792 - 161,797,481 (-)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Scube2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1563998
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.