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Gene: Edaradd (EDAR-associated death domain) Rattus norvegicus
Symbol: Edaradd
Name: EDAR-associated death domain
Description: Involved in positive regulation of NIK/NF-kappaB signaling. Used to study hypohidrotic ectodermal dysplasia and otitis media. Human ortholog(s) of this gene implicated in ectodermal dysplasia 11A and ectodermal dysplasia 11B. Orthologous to human EDARADD (EDAR associated death domain); INTERACTS WITH 17beta-estradiol; bisphenol A; 3-isobutyl-1-methyl-7H-xanthine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: ectodysplasin-A receptor-associated adapter protein; EDAR (ectodysplasin-A receptor)-associated death domain; LOC498769; RGD1564010; similar to crinkled
Homo sapiens (human) : EDARADD (EDAR associated death domain)  HGNC  Alliance
Mus musculus (house mouse) : Edaradd (EDAR (ectodysplasin-A receptor)-associated death domain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Edaradd (EDAR associated death domain)
Pan paniscus (bonobo/pygmy chimpanzee) : EDARADD (EDAR associated death domain)
Canis lupus familiaris (dog) : EDARADD (EDAR associated death domain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Edaradd (EDAR associated death domain)
Sus scrofa (pig) : EDARADD (EDAR associated death domain)
Chlorocebus sabaeus (African green monkey) : EDARADD (EDAR associated death domain)
Heterocephalus glaber (naked mole-rat) : Edaradd (EDAR associated death domain)
more info ...
Allele / Splice: EdaraddswhKyo  
Genetic Models: WTC-swh/Kyo
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01790,802,280 - 90,843,476 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1790,802,393 - 90,843,485 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01792,462,305 - 92,503,399 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41767,056,373 - 67,143,933 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1785,700,726 - 85,744,668 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Edaradd
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564010
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.