Gene: Lats1 (large tumor suppressor kinase 1) Rattus norvegicus
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Symbol: Lats1
Name: large tumor suppressor kinase 1
Description: Predicted to have several functions, including ATP binding activity, estrogen receptor binding activity, and magnesium ion binding activity; predicted to be involved in several processes, including animal organ development, inner cell mass cell differentiation, and regulation of protein metabolic process; predicted to localize to the spindle pole; orthologous to human LATS1 (large tumor suppressor kinase 1); INTERACTS WITH bisphenol A; Monobutylphthalate; vinclozolin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypothetical protein LOC308265; LATS, large tumor suppressor, homolog 1; LATS, large tumor suppressor, homolog 1 (Drosophila); LOC308265; RGD1564085; serine/threonine-protein kinase LATS1; similar to LATS homolog 1
Orthologs:
Homo sapiens (human) : LATS1 (large tumor suppressor kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Lats1 (large tumor suppressor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lats1 (large tumor suppressor kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LATS1 (large tumor suppressor kinase 1)
Canis lupus familiaris (dog) : LATS1 (large tumor suppressor kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lats1 (large tumor suppressor kinase 1)
Sus scrofa (pig) : LATS1 (large tumor suppressor kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.011,784,078 - 1,817,310 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013,480,828 - 3,514,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.412,375,233 - 2,383,106 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1708,453 - 741,716 (+)NCBICelera
Cytogenetic Map1p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lats1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564085
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.