Gene: Lats1 (large tumor suppressor kinase 1) Rattus norvegicus
Symbol: Lats1
Name: large tumor suppressor kinase 1
Description: Predicted to have several functions, including ATP binding activity, estrogen receptor binding activity, and magnesium ion binding activity; predicted to be involved in several processes, including animal organ development, inner cell mass cell differentiation, and regulation of protein metabolic process; predicted to localize to the spindle pole; orthologous to human LATS1 (large tumor suppressor kinase 1); INTERACTS WITH bisphenol A; Monobutylphthalate; vinclozolin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypothetical protein LOC308265; LATS, large tumor suppressor, homolog 1; LATS, large tumor suppressor, homolog 1 (Drosophila); LOC308265; RGD1564085; serine/threonine-protein kinase LATS1; similar to LATS homolog 1
Homo sapiens (human) : LATS1 (large tumor suppressor kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Lats1 (large tumor suppressor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lats1 (large tumor suppressor kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LATS1 (large tumor suppressor kinase 1)
Canis lupus familiaris (dog) : LATS1 (large tumor suppressor kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lats1 (large tumor suppressor kinase 1)
Sus scrofa (pig) : LATS1 (large tumor suppressor kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.011,784,078 - 1,817,310 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013,480,828 - 3,514,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.412,375,233 - 2,383,106 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1708,453 - 741,716 (+)NCBICelera
Cytogenetic Map1p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Lats1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564085
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.