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Gene: Hhip (Hedgehog-interacting protein) Rattus norvegicus
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Symbol: Hhip
Name: Hedgehog-interacting protein
Description: Predicted to have hedgehog family protein binding activity and zinc ion binding activity. Involved in negative regulation of apoptotic process. Localizes to the cytoplasm; nucleus; and plasma membrane. Biomarker of diabetic neuropathy and primary biliary cirrhosis. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to human HHIP (hedgehog interacting protein); PARTICIPATES IN Hedgehog signaling pathway; basal cell carcinoma pathway; INTERACTS WITH 6-propyl-2-thiouracil; aristolochic acid; chloroprene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Hedgehog-interacting protein-like; LOC291936; RGD1564108; similar to hedgehog-interacting protein
Orthologs:
Homo sapiens (human) : HHIP (hedgehog interacting protein)  HGNC  Alliance
Mus musculus (house mouse) : Hhip (Hedgehog-interacting protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hhip (hedgehog interacting protein)
Pan paniscus (bonobo/pygmy chimpanzee) : HHIP (hedgehog interacting protein)
Canis lupus familiaris (dog) : HHIP (hedgehog interacting protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hhip (hedgehog interacting protein)
Sus scrofa (pig) : HHIP (hedgehog interacting protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01931,525,134 - 31,614,487 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01942,430,120 - 42,518,700 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41929,752,595 - 29,840,439 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1927,371,896 - 27,460,078 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hhip
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564108
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.