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Gene: Tlx3 (T-cell leukemia, homeobox 3) Rattus norvegicus
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Symbol: Tlx3
Name: T-cell leukemia, homeobox 3
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including nervous system development; regulation of respiratory gaseous exchange by nervous system process; and respiratory gaseous exchange by respiratory system. Predicted to localize to nucleoplasm. Orthologous to human TLX3 (T cell leukemia homeobox 3); INTERACTS WITH 6-propyl-2-thiouracil; sodium dichromate; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC497881; RGD1564190; similar to HOX11L2; T-cell leukemia homeobox protein 3
Orthologs:
Homo sapiens (human) : TLX3 (T cell leukemia homeobox 3)  HGNC  Alliance
Mus musculus (house mouse) : Tlx3 (T cell leukemia, homeobox 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlx3 (T cell leukemia homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TLX3 (T cell leukemia homeobox 3)
Canis lupus familiaris (dog) : TLX3 (T cell leukemia homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlx3 (T cell leukemia homeobox 3)
Sus scrofa (pig) : TLX3 (T cell leukemia homeobox 3)
Chlorocebus sabaeus (African green monkey) : TLX3 (T cell leukemia homeobox 3)
Heterocephalus glaber (naked mole-rat) : Tlx3 (T cell leukemia homeobox 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01018,128,869 - 18,131,745 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,129,408 - 18,131,562 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01018,012,959 - 18,015,778 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41018,100,105 - 18,102,910 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1017,429,807 - 17,432,683 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tlx3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564190
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.