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Gene: Tlx3 (T-cell leukemia, homeobox 3) Rattus norvegicus
Symbol: Tlx3
Name: T-cell leukemia, homeobox 3
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including nervous system development; regulation of respiratory gaseous exchange by nervous system process; and respiratory gaseous exchange by respiratory system. Predicted to localize to nucleoplasm. Orthologous to human TLX3 (T cell leukemia homeobox 3); INTERACTS WITH 6-propyl-2-thiouracil; sodium dichromate; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC497881; RGD1564190; similar to HOX11L2; T-cell leukemia homeobox protein 3
Homo sapiens (human) : TLX3 (T cell leukemia homeobox 3)  HGNC  Alliance
Mus musculus (house mouse) : Tlx3 (T cell leukemia, homeobox 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlx3 (T cell leukemia homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TLX3 (T cell leukemia homeobox 3)
Canis lupus familiaris (dog) : TLX3 (T cell leukemia homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlx3 (T cell leukemia homeobox 3)
Sus scrofa (pig) : TLX3 (T cell leukemia homeobox 3)
Chlorocebus sabaeus (African green monkey) : TLX3 (T cell leukemia homeobox 3)
Heterocephalus glaber (naked mole-rat) : Tlx3 (T cell leukemia homeobox 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01018,128,869 - 18,131,745 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,129,408 - 18,131,562 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01018,012,959 - 18,015,778 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41018,100,105 - 18,102,910 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1017,429,807 - 17,432,683 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tlx3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564190
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.