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Gene: Hmgb3 (high mobility group box 3) Rattus norvegicus
Symbol: Hmgb3
Name: high mobility group box 3
Description: Predicted to have nucleic acid binding activity and transcription factor binding activity. Predicted to be involved in several processes, including chromosome organization; negative regulation of hemopoiesis; and positive regulation of innate immune response. Predicted to localize to cytoplasm and nuclear chromatin. Human ortholog(s) of this gene implicated in syndromic microphthalmia 13. Orthologous to human HMGB3 (high mobility group box 3); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; chlorpyrifos.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: high mobility group protein B3; LOC305373; RGD1564407; similar to high mobility group protein homolog HMG4
Homo sapiens (human) : HMGB3 (high mobility group box 3)  HGNC  Alliance
Mus musculus (house mouse) : Hmgb3 (high mobility group box 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hmgb3 (high mobility group box 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HMGB3 (high mobility group box 3)
Canis lupus familiaris (dog) : HMGB3 (high mobility group box 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmgb3 (high mobility group box 3)
Sus scrofa (pig) : HMGB3 (high mobility group box 3)
Heterocephalus glaber (naked mole-rat) : Hmgb3 (high mobility group box 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01736,690,190 - 36,694,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1736,690,249 - 36,694,325 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1451,458,443 - 51,462,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01451,617,771 - 51,622,052 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X157,027,845 - 157,033,080 (+)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Hmgb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564407
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.