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Gene: Smcr8 (SMCR8-C9orf72 complex subunit) Rattus norvegicus
Symbol: Smcr8
Name: SMCR8-C9orf72 complex subunit
CRRD ID: 1564621
Description: Predicted to contribute to Rab guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of macromolecule metabolic process; regulation of TOR signaling; and regulation of macroautophagy. Predicted to localize to several cellular components, including Atg1/ULK1 kinase complex; guanyl-nucleotide exchange factor complex; and nucleoplasm. Orthologous to human SMCR8 (SMCR8-C9orf72 complex subunit); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: INFERRED
Also known as: LOC497918; RGD1564621; similar to Smcr8 protein; Smith-Magenis syndrome chromosome region, candidate 8; Smith-Magenis syndrome chromosome region, candidate 8 homolog; Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
Homo sapiens (human) : SMCR8 (SMCR8-C9orf72 complex subunit)  HGNC  Alliance
Mus musculus (house mouse) : Smcr8 (Smith-Magenis syndrome chromosome region, candidate 8 homolog (human))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smcr8 (SMCR8-C9orf72 complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SMCR8 (SMCR8-C9orf72 complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smcr8 (SMCR8-C9orf72 complex subunit)
Sus scrofa (pig) : SMCR8 (SMCR8-C9orf72 complex subunit)
Chlorocebus sabaeus (African green monkey) : SMCR8 (SMCR8-C9orf72 complex subunit)
Heterocephalus glaber (naked mole-rat) : Smcr8 (SMCR8-C9orf72 complex subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01047,019,326 - 47,026,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,018,974 - 47,026,465 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,791,502 - 46,798,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,924,224 - 46,931,363 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1044,712,528 - 44,719,666 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Smcr8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564621
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.