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Gene: Smcr8 (SMCR8-C9orf72 complex subunit) Rattus norvegicus
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Symbol: Smcr8
Name: SMCR8-C9orf72 complex subunit
Description: Predicted to contribute to Rab guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of macromolecule metabolic process; regulation of TOR signaling; and regulation of macroautophagy. Predicted to colocalize with the Atg1/ULK1 kinase complex. Orthologous to human SMCR8 (SMCR8-C9orf72 complex subunit); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; 2,2',4,4'-Tetrabromodiphenyl ether (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Also known as: LOC497918; RGD1564621; similar to Smcr8 protein; Smith-Magenis syndrome chromosome region, candidate 8; Smith-Magenis syndrome chromosome region, candidate 8 homolog; Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
Orthologs:
Homo sapiens (human) : SMCR8 (SMCR8-C9orf72 complex subunit)  HGNC  Alliance
Mus musculus (house mouse) : Smcr8 (Smith-Magenis syndrome chromosome region, candidate 8 homolog (human))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smcr8 (SMCR8-C9orf72 complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SMCR8 (SMCR8-C9orf72 complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smcr8 (SMCR8-C9orf72 complex subunit)
Sus scrofa (pig) : SMCR8 (SMCR8-C9orf72 complex subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01047,019,326 - 47,026,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01046,791,502 - 46,798,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,924,224 - 46,931,363 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1044,712,528 - 44,719,666 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Smcr8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564621
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.