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Gene: Ddx3x (DEAD-box helicase 3, X-linked) Rattus norvegicus
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Symbol: Ddx3x
Name: DEAD-box helicase 3, X-linked
Description: Predicted to have several functions, including eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and nucleoside-triphosphatase activity. Predicted to be involved in several processes, including positive regulation of type I interferon production; regulation of cellular protein metabolic process; and regulation of signal transduction. Predicted to colocalize with cytosolic small ribosomal subunit and eukaryotic translation initiation factor 3 complex. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to several human genes including DDX3X (DEAD-box helicase 3 X-linked); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-dependent RNA helicase DDX3X; DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
Orthologs:
Homo sapiens (human) : DDX3X (DEAD-box helicase 3 X-linked)  HGNC  Alliance
Mus musculus (house mouse) : Ddx3x (DEAD box helicase 3, X-linked)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx3x (DEAD-box helicase 3 X-linked)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX3X (DEAD-box helicase 3, X-linked)
Canis lupus familiaris (dog) : DDX3X (DEAD-box helicase 3 X-linked)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx3x (DEAD-box helicase 3 X-linked)
Sus scrofa (pig) : DDX3X (DEAD-box helicase 3 X-linked)
Chlorocebus sabaeus (African green monkey) : DDX3X (DEAD-box helicase 3 X-linked)
Heterocephalus glaber (naked mole-rat) : Ddx3x (DEAD-box helicase 3 X-linked)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X10,400,363 - 10,414,010 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX10,400,366 - 10,413,995 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X11,198,745 - 11,212,383 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X21,495,072 - 21,508,690 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX10,011,280 - 10,024,898 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ddx3x
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564771
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.