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Gene: Wrn (WRN RecQ like helicase) Rattus norvegicus
Symbol: Wrn
Name: WRN RecQ like helicase
CRRD ID: 1564788
Description: Exhibits chromatin binding activity. Involved in brain development. Localizes to neuron projection. Human ortholog(s) of this gene implicated in Werner syndrome; breast cancer; coronary artery disease (multiple); diffuse scleroderma; and senile cataract. Orthologous to human WRN (WRN RecQ like helicase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; cisplatin; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC290805; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome RecQ like helicase; Werner syndrome, RecQ helicase-like
Homo sapiens (human) : WRN (WRN RecQ like helicase)  HGNC  Alliance
Mus musculus (house mouse) : Wrn (Werner syndrome RecQ like helicase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wrn (WRN RecQ like helicase)
Pan paniscus (bonobo/pygmy chimpanzee) : WRN (WRN RecQ like helicase)
Canis lupus familiaris (dog) : WRN (WRN RecQ like helicase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wrn (WRN RecQ like helicase)
Sus scrofa (pig) : WRN (WRN RecQ like helicase)
Chlorocebus sabaeus (African green monkey) : WRN (WRN RecQ like helicase)
Heterocephalus glaber (naked mole-rat) : Wrn (WRN RecQ like helicase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01662,483,773 - 62,619,018 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1662,483,761 - 62,615,375 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01662,148,560 - 62,283,748 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41662,535,144 - 62,668,700 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1656,796,927 - 56,929,877 (+)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Wrn
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1564788
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.