Gene: Shb (SH2 domain containing adaptor protein B) Rattus norvegicus
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Symbol: Shb
Name: SH2 domain containing adaptor protein B
Description: Predicted to have phosphotyrosine residue binding activity; predicted to be involved in several processes, including B cell proliferation, blood vessel morphogenesis, and positive regulation of immune response; predicted to localize to the cytoplasmic ribonucleoprotein granule, cytosol, and nucleoplasm; orthologous to human SHB (SH2 domain containing adaptor protein B); PARTICIPATES IN platelet-derived growth factor signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; decabromodiphenyl ether; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC362513; RGD1565350; SH2 domain-containing adapter protein B; similar to Shb protein; Src homology 2 domain containing adaptor protein B
Orthologs:
Homo sapiens (human) : SHB (SH2 domain containing adaptor protein B)  HGNC  Alliance
Mus musculus (house mouse) : Shb (src homology 2 domain-containing transforming protein B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shb (SH2 domain containing adaptor protein B)
Pan paniscus (bonobo/pygmy chimpanzee) : SHB (SH2 domain containing adaptor protein B)
Canis lupus familiaris (dog) : SHB (SH2 domain containing adaptor protein B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shb (SH2 domain containing adaptor protein B)
Sus scrofa (pig) : SHB (SH2 domain containing adaptor protein B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0560,970,650 - 61,077,881 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0565,479,290 - 65,587,205 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4561,983,643 - 62,090,620 (-)NCBIRGSC3.4rn4RGSC3.4
Celera558,246,193 - 58,353,269 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Shb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1565350
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.