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Gene: Glis3 (GLIS family zinc finger 3) Rattus norvegicus
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Symbol: Glis3
Name: GLIS family zinc finger 3
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and transcription by RNA polymerase II. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in neonatal diabetes mellitus with congenital hypothyroidism. Orthologous to human GLIS3 (GLIS family zinc finger 3); INTERACTS WITH 1-naphthyl isothiocyanate; (-)-epigallocatechin 3-gallate (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: hypothetical protein LOC680671; hypothetical protein LOC687614; LOC293882; LOC680671; RGD1565505; similar to Zinc finger protein GLIS3 (GLI-similar 3); zinc finger protein GLIS3
Orthologs:
Homo sapiens (human) : GLIS3 (GLIS family zinc finger 3)  HGNC  Alliance
Mus musculus (house mouse) : Glis3 (GLIS family zinc finger 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glis3 (GLIS family zinc finger 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GLIS3 (GLIS family zinc finger 3)
Canis lupus familiaris (dog) : GLIS3 (GLIS family zinc finger 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glis3 (GLIS family zinc finger 3)
Sus scrofa (pig) : GLIS3 (GLIS family zinc finger 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01246,380,816 - 246,564,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01253,622,178 - 254,039,761 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,291,906 - 232,306,168 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.41231,881,983 - 232,292,288 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1223,130,737 - 223,177,831 (-)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Glis3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1565505
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.