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Gene: Setx (senataxin) Rattus norvegicus
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Symbol: Setx
Name: senataxin
Description: Predicted to have RNA binding activity; identical protein binding activity; and transcription termination site sequence-specific DNA binding activity. Predicted to be involved in several processes, including intracellular signal transduction; nucleic acid metabolic process; and positive regulation of RNA metabolic process. Predicted to localize to several cellular components, including the growth cone; intercellular bridge; and nuclear lumen. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4 and ataxia with oculomotor apraxia type 2. Orthologous to human SETX (senataxin); INTERACTS WITH amphetamine; bisphenol A; DDT.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DEAxQ-box helicase; LOC362096; LOW QUALITY PROTEIN: probable helicase senataxin; probable helicase senataxin; RGD1565575; similar to senataxin; tRNA splicing endonuclease regulator 1
Orthologs:
Homo sapiens (human) : SETX (senataxin)  HGNC  Alliance
Mus musculus (house mouse) : Setx (senataxin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Setx (senataxin)
Pan paniscus (bonobo/pygmy chimpanzee) : SETX (senataxin)
Canis lupus familiaris (dog) : SETX (senataxin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Setx (senataxin)
Sus scrofa (pig) : SETX (senataxin)
Chlorocebus sabaeus (African green monkey) : SETX (senataxin)
Heterocephalus glaber (naked mole-rat) : Setx (senataxin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.037,680,430 - 7,731,815 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,686,503 - 7,730,539 (+)Ensembl
Rnor_5.0313,029,002 - 13,080,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.438,113,749 - 8,156,463 (+)NCBIRGSC3.4rn4RGSC3.4
Celera37,210,020 - 7,259,874 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Setx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1565575
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.