Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kdm5b (lysine demethylase 5B) Rattus norvegicus
Analyze
Symbol: Kdm5b
Name: lysine demethylase 5B
Description: Predicted to have several functions, including histone demethylase activity (H3-K4 specific); transcription corepressor activity; and zinc ion binding activity. Involved in cellular response to fibroblast growth factor stimulus; lens fiber cell differentiation; and response to fungicide. Predicted to localize to the cytosol and histone methyltransferase complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability; breast cancer; and malignant glioma. Orthologous to human KDM5B (lysine demethylase 5B); PARTICIPATES IN histone modification pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; chlorpyrifos.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Jarid1b; jumonji, AT rich interactive domain 1B; jumonji, AT rich interactive domain 1B (Rbp2 like); Jumonji, AT rich interactive domain 1B (RBP2-like); LOC304809; lysine (K)-specific demethylase 5B; lysine-specific demethylase 5B; RGD1565602; similar to PLU1
Orthologs:
Homo sapiens (human) : KDM5B (lysine demethylase 5B)  HGNC  Alliance
Mus musculus (house mouse) : Kdm5b (lysine (K)-specific demethylase 5B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5b (lysine demethylase 5B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5B (lysine demethylase 5B)
Canis lupus familiaris (dog) : KDM5B (lysine demethylase 5B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5b (lysine demethylase 5B)
Sus scrofa (pig) : KDM5B (lysine demethylase 5B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01351,384,371 - 51,455,392 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01356,438,019 - 56,509,593 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,502,602 - 47,576,946 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1346,328,788 - 46,400,255 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Kdm5b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1565602
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.