Gene: Sox2 (SRY box 2) Rattus norvegicus
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Symbol: Sox2
Name: SRY box 2
Description: Exhibits transcription regulatory region sequence-specific DNA binding activity; contributes to DNA-binding transcription activator activity, RNA polymerase II-specific; involved in several processes, including adenohypophysis development, positive regulation of cell differentiation, and positive regulation of cell-cell adhesion; localizes to the nucleus; orthologous to human SOX2 (SRY-box 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC100912162; LOC499593; RGD1565646; similar to SOX2 protein; SRY (sex determining region Y)-box 2; SRY-box containing gene 2; transcription factor SOX-2; uncharacterized LOC100912162
Orthologs:
Homo sapiens (human) : SOX2 (SRY-box 2)  HGNC  Alliance
Mus musculus (house mouse) : Sox2 (SRY (sex determining region Y)-box 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox2 (SRY-box 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX2 (SRY-box 2)
Canis lupus familiaris (dog) : SOX2 (SRY-box 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox2 (SRY-box 2)
Sus scrofa (pig) : SOX2 (SRY-box 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02121,165,137 - 121,167,545 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02140,810,593 - 140,813,001 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42120,969,021 - 120,971,430 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2112,569,723 - 112,572,132 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sox2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1565646
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.