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Gene: Vav3 (vav guanine nucleotide exchange factor 3) Rattus norvegicus
Symbol: Vav3
Name: vav guanine nucleotide exchange factor 3
Description: Predicted to have Rac guanyl-nucleotide exchange factor activity and epidermal growth factor receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; neutrophil chemotaxis; and positive regulation of B cell proliferation. Predicted to localize to the cytoplasm and plasma membrane. Orthologous to human VAV3 (vav guanine nucleotide exchange factor 3); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; Fc epsilon receptor mediated signaling pathway; B cell receptor signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; aflatoxin B1.
Type: protein-coding
Also known as: guanine nucleotide exchange factor VAV3; LOC295378; RGD1565941; similar to Vav 3 oncogene; vav 3 guanine nucleotide exchange factor; vav 3 oncogene
Homo sapiens (human) : VAV3 (vav guanine nucleotide exchange factor 3)  HGNC  Alliance
Mus musculus (house mouse) : Vav3 (vav 3 oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vav3 (vav guanine nucleotide exchange factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : VAV3 (vav guanine nucleotide exchange factor 3)
Canis lupus familiaris (dog) : VAV3 (vav guanine nucleotide exchange factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vav3 (vav guanine nucleotide exchange factor 3)
Sus scrofa (pig) : VAV3 (vav guanine nucleotide exchange factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02212,247,061 - 212,585,818 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2212,247,451 - 212,585,818 (+)Ensembl
Rnor_5.02231,716,228 - 232,053,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,982,222 - 205,326,505 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2189,650,820 - 189,990,562 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Vav3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1565941
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.