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Gene: Vav3 (vav guanine nucleotide exchange factor 3) Rattus norvegicus
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Symbol: Vav3
Name: vav guanine nucleotide exchange factor 3
Description: Predicted to have Rac guanyl-nucleotide exchange factor activity and epidermal growth factor receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; neutrophil chemotaxis; and positive regulation of B cell proliferation. Predicted to localize to the cytoplasm and plasma membrane. Orthologous to human VAV3 (vav guanine nucleotide exchange factor 3); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; Fc epsilon receptor mediated signaling pathway; B cell receptor signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: guanine nucleotide exchange factor VAV3; LOC295378; RGD1565941; similar to Vav 3 oncogene; vav 3 guanine nucleotide exchange factor; vav 3 oncogene
Orthologs:
Homo sapiens (human) : VAV3 (vav guanine nucleotide exchange factor 3)  HGNC  Alliance
Mus musculus (house mouse) : Vav3 (vav 3 oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vav3 (vav guanine nucleotide exchange factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : VAV3 (vav guanine nucleotide exchange factor 3)
Canis lupus familiaris (dog) : VAV3 (vav guanine nucleotide exchange factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vav3 (vav guanine nucleotide exchange factor 3)
Sus scrofa (pig) : VAV3 (vav guanine nucleotide exchange factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02212,247,061 - 212,585,818 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2212,247,451 - 212,585,818 (+)Ensembl
Rnor_5.02231,716,228 - 232,053,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,982,222 - 205,326,505 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2189,650,820 - 189,990,562 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Vav3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1565941
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.