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Gene: Frem2 (FRAS1 related extracellular matrix 2) Rattus norvegicus
Symbol: Frem2
Name: FRAS1 related extracellular matrix 2
Description: Predicted to be involved in animal organ development; embryonic digit morphogenesis; and morphogenesis of an epithelium. Predicted to localize to the basement membrane. Used to study Fraser syndrome. Human ortholog(s) of this gene implicated in Fraser syndrome. Orthologous to human FREM2 (FRAS1 related extracellular matrix 2); INTERACTS WITH 1-naphthyl isothiocyanate; 3-chloropropane-1,2-diol; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Fras1 related extracellular matrix protein 2; FRAS1-related extracellular matrix protein 2; LOC310418; RGD1566012; similar to OTTHUMP00000018288
Homo sapiens (human) : FREM2 (FRAS1 related extracellular matrix 2)  HGNC  Alliance
Mus musculus (house mouse) : Frem2 (Fras1 related extracellular matrix protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Frem2 (FRAS1 related extracellular matrix 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FREM2 (FRAS1 related extracellular matrix 2)
Canis lupus familiaris (dog) : FREM2 (FRAS1 related extracellular matrix 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Frem2 (FRAS1 related extracellular matrix 2)
Sus scrofa (pig) : FREM2 (FRAS1 related extracellular matrix 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02142,747,501 - 142,885,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02162,430,795 - 162,568,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42142,464,169 - 142,604,059 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2132,100,362 - 132,238,927 (-)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Frem2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1566012
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.