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Gene: Frem2 (FRAS1 related extracellular matrix 2) Rattus norvegicus
Symbol: Frem2
Name: FRAS1 related extracellular matrix 2
CRRD ID: 1566012
Description: Predicted to be involved in several processes, including animal organ development; cell adhesion; and embryonic digit morphogenesis. Predicted to localize to basement membrane. Used to study Fraser syndrome 2. Human ortholog(s) of this gene implicated in Fraser syndrome 2 and isolated cryptophthalmia. Orthologous to human FREM2 (FRAS1 related extracellular matrix 2); INTERACTS WITH 1-naphthyl isothiocyanate; 3-chloropropane-1,2-diol; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Fras1 related extracellular matrix protein 2; FRAS1-related extracellular matrix protein 2; LOC310418; RGD1566012; similar to OTTHUMP00000018288
Homo sapiens (human) : FREM2 (FRAS1 related extracellular matrix 2)  HGNC  Alliance
Mus musculus (house mouse) : Frem2 (Fras1 related extracellular matrix protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Frem2 (FRAS1 related extracellular matrix 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FREM2 (FRAS1 related extracellular matrix 2)
Canis lupus familiaris (dog) : FREM2 (FRAS1 related extracellular matrix 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Frem2 (FRAS1 related extracellular matrix 2)
Sus scrofa (pig) : FREM2 (FRAS1 related extracellular matrix 2)
Chlorocebus sabaeus (African green monkey) : FREM2 (FRAS1 related extracellular matrix 2)
Heterocephalus glaber (naked mole-rat) : Frem2 (FRAS1 related extracellular matrix 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02142,747,501 - 142,885,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2142,747,501 - 142,885,604 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02162,430,795 - 162,568,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42142,464,169 - 142,604,059 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2132,100,362 - 132,238,927 (-)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Frem2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1566012
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.