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Gene: Grb10 (growth factor receptor bound protein 10) Rattus norvegicus
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Symbol: Grb10
Name: growth factor receptor bound protein 10
Description: Exhibits insulin receptor binding activity. Involved in insulin receptor signaling pathway; negative regulation of glycogen biosynthetic process; and positive regulation of phosphorylation. Predicted to localize to the protein-containing complex. Orthologous to human GRB10 (growth factor receptor bound protein 10); PARTICIPATES IN insulin signaling pathway; insulin-like growth factor signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GRB10 adapter protein; Growth factor receptor-bound protein 10; LOC498416; RGD1566234; similar to Grb10 protein
Orthologs:
Homo sapiens (human) : GRB10 (growth factor receptor bound protein 10)  HGNC  Alliance
Mus musculus (house mouse) : Grb10 (growth factor receptor bound protein 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb10 (growth factor receptor bound protein 10)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB10 (growth factor receptor bound protein 10)
Canis lupus familiaris (dog) : GRB10 (growth factor receptor bound protein 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb10 (growth factor receptor bound protein 10)
Sus scrofa (pig) : GRB10 (growth factor receptor bound protein 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01492,021,851 - 92,122,249 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01491,818,383 - 91,914,937 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41492,814,797 - 92,911,442 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1485,495,882 - 85,591,916 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Grb10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1566234
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.