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Gene: Piezo2 (piezo-type mechanosensitive ion channel component 2) Rattus norvegicus
Symbol: Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Description: Predicted to have cation channel activity and mechanosensitive ion channel activity. Predicted to be involved in several processes, including cellular response to mechanical stimulus; detection of mechanical stimulus involved in sensory perception; and regulation of membrane potential. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Fam38b; family with sequence similarity 38, member B; LOC307380; LOC688934; RGD1306866; similar to Hypothetical protein KIAA0233; similar to protein fam38b
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01858,353,361 - 58,728,555 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1858,354,648 - 58,499,836 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01857,576,278 - 57,949,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41859,147,791 - 59,531,873 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11859,220,826 - 59,402,111 (-)NCBI
Celera1854,616,241 - 54,988,723 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Piezo2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1582973
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.