Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ephb4 (EPH receptor B4) Rattus norvegicus
Symbol: Ephb4
Name: EPH receptor B4
Description: Predicted to have ephrin receptor activity. Predicted to be involved in several processes, including circulatory system development; positive regulation of T cell costimulation; and positive regulation of aorta morphogenesis. Predicted to localize to integral component of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human EPHB4 (EPH receptor B4); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 1H-1,2,4-triazole; bisphenol A; cocaine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: ephrin type-B receptor 4; LOC686310; similar to Ephrin type-B receptor 4 precursor (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1)
Homo sapiens (human) : EPHB4 (EPH receptor B4)  HGNC  Alliance
Mus musculus (house mouse) : Ephb4 (Eph receptor B4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephb4 (EPH receptor B4)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHB4 (EPH receptor B4)
Canis lupus familiaris (dog) : EPHB4 (EPH receptor B4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephb4 (EPH receptor B4)
Sus scrofa (pig) : EPHB4 (EPH receptor B4)
Chlorocebus sabaeus (African green monkey) : EPHB4 (EPH receptor B4)
Heterocephalus glaber (naked mole-rat) : Ephb4 (EPH receptor B4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01222,393,338 - 22,418,332 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,393,330 - 22,417,980 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,407,927 - 24,432,912 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1221,128,289 - 21,153,496 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ephb4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1583193
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.