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Gene: Sp3 (Sp3 transcription factor) Rattus norvegicus
Symbol: Sp3
Name: Sp3 transcription factor
CRRD ID: 1583765
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated. Localizes to nucleus; protein-DNA complex; and transcription repressor complex. Orthologous to human SP3 (Sp3 transcription factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Sp3 transcription factor (mapped); Sp3_mapped; trans-acting transcription factor 3; transcription factor Sp3
Homo sapiens (human) : SP3 (Sp3 transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Sp3 (trans-acting transcription factor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp3 (Sp3 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP3 (Sp3 transcription factor)
Canis lupus familiaris (dog) : SP3 (Sp3 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp3 (Sp3 transcription factor)
Sus scrofa (pig) : SP3 (Sp3 transcription factor)
Chlorocebus sabaeus (African green monkey) : SP3 (Sp3 transcription factor)
Heterocephalus glaber (naked mole-rat) : Sp3 (Sp3 transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0359,644,579 - 59,689,011 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl359,646,015 - 59,688,692 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0366,729,636 - 66,739,419 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0366,118,151 - 66,163,940 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4355,440,985 - 55,485,768 (-)NCBIRGSC3.4rn4RGSC3.4
Celera357,350,925 - 57,387,172 (-)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sp3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1583765
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.