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Gene: Oxct1 (3-oxoacid CoA transferase 1) Rattus norvegicus
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Symbol: Oxct1
Name: 3-oxoacid CoA transferase 1
Description: Exhibits 3-oxoacid CoA-transferase activity and identical protein binding activity. Involved in several processes, including animal organ development; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and response to ethanol. Localizes to mitochondrion. Biomarker of obesity and type 2 diabetes mellitus. Orthologous to human OXCT1 (3-oxoacid CoA-transferase 1); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-oxoacid CoA-transferase 1; 3-oxoacid-CoA transferase 1; LOC100359544; LOC690163; MGC187935; SCOT; scot-S; similar to 3-oxoacid CoA transferase 1; somatic-type succinyl CoA:3-oxoacid CoA-transferase; somatic-type succinyl-CoA:3-oxoacid CoA-transferase; succinyl-CoA:3-ketoacid CoA transferase; succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial-like
Orthologs:
Homo sapiens (human) : OXCT1 (3-oxoacid CoA-transferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Oxct1 (3-oxoacid CoA transferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oxct1 (3-oxoacid CoA-transferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OXCT1 (3-oxoacid CoA-transferase 1)
Canis lupus familiaris (dog) : OXCT1 (3-oxoacid CoA-transferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oxct1 (3-oxoacid CoA-transferase 1)
Sus scrofa (pig) : OXCT1 (3-oxoacid CoA-transferase 1)
Chlorocebus sabaeus (African green monkey) : OXCT1 (3-oxoacid CoA-transferase 1)
Heterocephalus glaber (naked mole-rat) : Oxct1 (3-oxoacid CoA-transferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0253,859,738 - 54,007,733 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl253,859,737 - 54,007,756 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0272,891,713 - 73,037,617 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4253,189,358 - 53,217,848 (+)NCBIRGSC3.4rn4RGSC3.4
Celera248,914,408 - 49,050,216 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Oxct1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1584008
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.