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Gene: Ppm1m (protein phosphatase, Mg2+/Mn2+ dependent, 1M) Rattus norvegicus
Symbol: Ppm1m
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1M
Description: Predicted to have [pyruvate dehydrogenase (lipoamide)] phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; and manganese ion binding activity. Predicted to be involved in positive regulation of pyruvate dehydrogenase activity and protein dephosphorylation. Predicted to localize to the mitochondrion and nucleus. Orthologous to human PPM1M (protein phosphatase, Mg2+/Mn2+ dependent 1M); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC686298; LOW QUALITY PROTEIN: protein phosphatase 1M; similar to protein phosphatase 2C eta isoform 2
Homo sapiens (human) : PPM1M (protein phosphatase, Mg2+/Mn2+ dependent 1M)  HGNC  Alliance
Mus musculus (house mouse) : Ppm1m (protein phosphatase 1M)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1m (protein phosphatase, Mg2+/Mn2+ dependent 1M)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1M (protein phosphatase, Mg2+/Mn2+ dependent 1M)
Canis lupus familiaris (dog) : PPM1M (protein phosphatase, Mg2+/Mn2+ dependent 1M)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1m (protein phosphatase, Mg2+/Mn2+ dependent 1M)
Sus scrofa (pig) : PPM1M (protein phosphatase, Mg2+/Mn2+ dependent 1M)
Chlorocebus sabaeus (African green monkey) : PPM1M (protein phosphatase, Mg2+/Mn2+ dependent 1M)
Heterocephalus glaber (naked mole-rat) : Ppm1m (protein phosphatase, Mg2+/Mn2+ dependent 1M)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08114,887,894 - 114,893,773 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8114,888,746 - 114,892,910 (-)Ensembl
Rnor_5.08114,252,089 - 114,257,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8106,159,262 - 106,164,333 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ppm1m
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1584266
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.