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Gene: Nkx3-2 (NK3 homeobox 2) Rattus norvegicus
Symbol: Nkx3-2
Name: NK3 homeobox 2
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including animal organ development; intestinal epithelial cell development; and negative regulation of chondrocyte differentiation. Orthologous to human NKX3-2 (NK3 homeobox 2); INTERACTS WITH bisphenol A; 17beta-hydroxy-5alpha-androstan-3-one (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: homeobox protein Nkx-3.2; LOC682329; LOW QUALITY PROTEIN: homeobox protein Nkx-3.2; similar to Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1)
Homo sapiens (human) : NKX3-2 (NK3 homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Nkx3-2 (NK3 homeobox 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx3-2 (NK3 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX3-2 (NK3 homeobox 2)
Canis lupus familiaris (dog) : NKX3-2 (NK3 homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx3-2 (NK3 homeobox 2)
Sus scrofa (pig) : NKX3-2 (NK3 homeobox 2)
Chlorocebus sabaeus (African green monkey) : NKX3-2 (NK3 homeobox 2)
Heterocephalus glaber (naked mole-rat) : Nkx3-2 (NK3 homeobox 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01473,813,531 - 73,818,489 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1473,813,528 - 73,815,757 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01473,825,360 - 73,828,802 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1468,115,963 - 68,118,823 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nkx3-2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1584617
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.