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Gene: Adam22 (ADAM metallopeptidase domain 22) Rattus norvegicus
Symbol: Adam22
Name: ADAM metallopeptidase domain 22
CRRD ID: 1585016
Description: Predicted to have metalloendopeptidase activity. Predicted to be involved in adult locomotory behavior; myelination in peripheral nervous system; and neurotransmitter receptor localization to postsynaptic specialization membrane. Predicted to localize to axon; glutamatergic synapse; and integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 61. Orthologous to human ADAM22 (ADAM metallopeptidase domain 22); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: a disintegrin and metalloprotease domain (ADAM) 22; a disintegrin and metalloprotease domain (ADAM) 22 (mapped); a disintegrin and metalloprotease domain 22; Adam22_mapped; disintegrin and metalloproteinase domain-containing protein 22; LOC683655; MDC2; similar to ADAM 22 precursor (A disintegrin and metalloproteinase domain 22)
Homo sapiens (human) : ADAM22 (ADAM metallopeptidase domain 22)  HGNC  Alliance
Mus musculus (house mouse) : Adam22 (a disintegrin and metallopeptidase domain 22)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adam22 (ADAM metallopeptidase domain 22)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM22 (ADAM metallopeptidase domain 22)
Canis lupus familiaris (dog) : ADAM22 (ADAM metallopeptidase domain 22)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam22 (ADAM metallopeptidase domain 22)
Sus scrofa (pig) : ADAM22 (ADAM metallopeptidase domain 22)
Chlorocebus sabaeus (African green monkey) : ADAM22 (ADAM metallopeptidase domain 22)
Heterocephalus glaber (naked mole-rat) : Adam22 (ADAM metallopeptidase domain 22)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0422,864,485 - 23,002,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl422,859,622 - 22,996,645 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0422,632,816 - 22,827,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0422,873,544 - 22,935,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4422,332,086 - 22,507,086 (-)NCBIRGSC3.4rn4RGSC3.4
Celera421,356,458 - 21,453,378 (+)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Adam22
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1585016
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.