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Gene: Arhgef4 (Rho guanine nucleotide exchange factor 4) Rattus norvegicus
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Symbol: Arhgef4
Name: Rho guanine nucleotide exchange factor 4
Description: Predicted to have Rac guanyl-nucleotide exchange factor activity and protein domain specific binding activity. Predicted to be involved in filopodium assembly and lamellipodium assembly. Orthologous to human ARHGEF4 (Rho guanine nucleotide exchange factor 4); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',5,5'-tetrachlorobiphenyl; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC301334; Rho guanine nucleotide exchange factor (GEF) 4; similar to Rho guanine nucleotide exchange factor 4 isoform a
Orthologs:
Homo sapiens (human) : ARHGEF4 (Rho guanine nucleotide exchange factor 4)  HGNC  Alliance
Mus musculus (house mouse) : Arhgef4 (Rho guanine nucleotide exchange factor (GEF) 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef4 (Rho guanine nucleotide exchange factor 4)
Canis lupus familiaris (dog) : ARHGEF4 (Rho guanine nucleotide exchange factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef4 (Rho guanine nucleotide exchange factor 4)
Sus scrofa (pig) : ARHGEF4 (Rho guanine nucleotide exchange factor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0941,160,562 - 41,305,015 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl941,295,909 - 41,302,501 (+)Ensembl
Rnor_5.0940,829,962 - 40,973,783 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4933,395,974 - 33,539,597 (+)NCBIRGSC3.4rn4RGSC3.4
Celera934,646,792 - 34,790,632 (+)NCBICelera
Cytogenetic Map9q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Arhgef4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1586179
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.