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Gene: Gdf2 (growth differentiation factor 2) Rattus norvegicus
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Symbol: Gdf2
Name: growth differentiation factor 2
Description: Predicted to have cytokine activity. Predicted to be involved in several processes, including positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; regulation of endothelial cell proliferation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia. Orthologous to human GDF2 (growth differentiation factor 2); INTERACTS WITH acetamide; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: growth/differentiation factor 2; LOC290921; similar to Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9)
Orthologs:
Homo sapiens (human) : GDF2 (growth differentiation factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Gdf2 (growth differentiation factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf2 (growth differentiation factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF2 (growth differentiation factor 2)
Canis lupus familiaris (dog) : GDF2 (growth differentiation factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf2 (growth differentiation factor 2)
Sus scrofa (pig) : GDF2 (growth differentiation factor 2)
Chlorocebus sabaeus (African green monkey) : GDF2 (growth differentiation factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01610,267,510 - 10,293,545 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,267,482 - 10,273,239 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,588,086 - 8,614,187 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera165,949,174 - 5,955,173 (-)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gdf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1586196
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.