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Gene: Cbx4 (chromobox 4) Rattus norvegicus
Symbol: Cbx4
Name: chromobox 4
Description: Predicted to have several functions, including SUMO binding activity; SUMO transferase activity; and nucleic acid binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and protein sumoylation. Predicted to localize to PRC1 complex and nuclear body. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human CBX4 (chromobox 4); PARTICIPATES IN histone modification pathway; INTERACTS WITH amphetamine; endosulfan; orphenadrine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: chromobox homolog 4; chromobox homolog 4 (Drosophila Pc class); chromobox homolog 4 (Pc class homolog, Drosophila); E3 SUMO-protein ligase CBX4; LOC501403; LOW QUALITY PROTEIN: E3 SUMO-protein ligase CBX4; similar to Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (MPc2)
Homo sapiens (human) : CBX4 (chromobox 4)  HGNC  Alliance
Mus musculus (house mouse) : Cbx4 (chromobox 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cbx4 (chromobox 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CBX4 (chromobox 4)
Canis lupus familiaris (dog) : CBX4 (chromobox 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cbx4 (chromobox 4)
Sus scrofa (pig) : CBX4 (chromobox 4)
Chlorocebus sabaeus (African green monkey) : CBX4 (chromobox 4)
Heterocephalus glaber (naked mole-rat) : Cbx4 (chromobox 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010108,190,947 - 108,196,455 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10108,190,995 - 108,196,217 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010107,803,761 - 107,809,306 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10102,881,315 - 102,890,183 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Cbx4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587243
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.