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Gene: Ext1 (exostosin glycosyltransferase 1) Rattus norvegicus
Symbol: Ext1
Name: exostosin glycosyltransferase 1
CRRD ID: 1587375
Description: Predicted to have UDP-glycosyltransferase activity and protein dimerization activity. Involved in brain development. Predicted to localize to Golgi apparatus; endoplasmic reticulum; and integral component of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in chondrosarcoma; hereditary multiple exostoses; and trichorhinophalangeal syndrome type II. Orthologous to human EXT1 (exostosin glycosyltransferase 1); PARTICIPATES IN heparan sulfate biosynthetic pathway; INTERACTS WITH bisphenol A; dibutyl phthalate; diuron.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: exostoses (multiple) 1; exostosin 1; exostosin-1; LOC299907; similar to Ext1
Homo sapiens (human) : EXT1 (exostosin glycosyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ext1 (exostosin glycosyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ext1 (exostosin glycosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EXT1 (exostosin glycosyltransferase 1)
Canis lupus familiaris (dog) : EXT1 (exostosin glycosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ext1 (exostosin glycosyltransferase 1)
Sus scrofa (pig) : EXT1 (exostosin glycosyltransferase 1)
Chlorocebus sabaeus (African green monkey) : EXT1 (exostosin glycosyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Ext1 (exostosin glycosyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0792,605,008 - 92,881,392 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl792,605,728 - 92,882,068 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0793,245,551 - 93,521,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4789,392,837 - 89,671,523 (-)NCBIRGSC3.4rn4RGSC3.4
Celera781,215,848 - 81,493,311 (-)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Ext1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587375
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.