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Gene: Ext1 (exostosin glycosyltransferase 1) Rattus norvegicus
Symbol: Ext1
Name: exostosin glycosyltransferase 1
Description: Predicted to have UDP-glycosyltransferase activity and protein dimerization activity. Involved in brain development. Predicted to localize to the Golgi apparatus; endoplasmic reticulum; and integral component of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in chondrosarcoma; hereditary multiple exostoses; and trichorhinophalangeal syndrome type II. Orthologous to human EXT1 (exostosin glycosyltransferase 1); PARTICIPATES IN heparan sulfate biosynthetic pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: exostoses (multiple) 1; exostosin 1; exostosin-1; LOC299907; similar to Ext1
Homo sapiens (human) : EXT1 (exostosin glycosyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ext1 (exostosin glycosyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ext1 (exostosin glycosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EXT1 (exostosin glycosyltransferase 1)
Canis lupus familiaris (dog) : EXT1 (exostosin glycosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ext1 (exostosin glycosyltransferase 1)
Sus scrofa (pig) : EXT1 (exostosin glycosyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0792,605,008 - 92,881,392 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0793,245,551 - 93,521,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4789,392,837 - 89,671,523 (-)NCBIRGSC3.4rn4RGSC3.4
Celera781,215,848 - 81,493,311 (-)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Ext1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587375
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.