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Gene: Spx (spexin hormone) Rattus norvegicus
Symbol: Spx
Name: spexin hormone
Description: Predicted to have neuropeptide hormone activity; type 2 galanin receptor binding activity; and type 3 galanin receptor binding activity. Involved in several processes, including long-chain fatty acid import into cell; negative regulation of appetite; and negative regulation of renal sodium excretion. Localizes to cytoplasm. Orthologous to human SPX (spexin hormone); INTERACTS WITH 17beta-estradiol; bisphenol A; 2,2',4,4'-Tetrabromodiphenyl ether (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypothetical protein LOC691138; liver regeneration-related protein LRRGT00060; LOC691138; LRRGT00060; neuropeptide Q; Npq; spexin
Homo sapiens (human) : SPX (spexin hormone)  HGNC  Alliance
Mus musculus (house mouse) : Spx (spexin hormone)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spx (spexin hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : SPX (spexin hormone)
Canis lupus familiaris (dog) : SPX (spexin hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spx (spexin hormone)
Sus scrofa (pig) : SPX (spexin hormone)
Chlorocebus sabaeus (African green monkey) : SPX (spexin hormone)
Heterocephalus glaber (naked mole-rat) : Spx (spexin hormone)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04176,629,597 - 176,635,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,629,800 - 176,641,008 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04240,843,758 - 240,849,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44179,975,336 - 179,980,842 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4163,888,558 - 163,894,628 (+)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Spx
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587448
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.