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Gene: Srsf1 (serine and arginine rich splicing factor 1) Rattus norvegicus
Symbol: Srsf1
Name: serine and arginine rich splicing factor 1
CRRD ID: 1587490
Description: Exhibits protein kinase B binding activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; liver regeneration; and positive regulation of RNA splicing. Localizes to cytoplasm and nucleus. Predicted to colocalize with exon-exon junction complex. Biomarker of hepatocellular carcinoma. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC689890; serine/arginine-rich splicing factor 1; Sfrs1; similar to splicing factor, arginine/serine-rich 1 (ASF/SF2); splicing factor, arginine/serine-rich 1; splicing factor, arginine/serine-rich 1B
Homo sapiens (human) : SRSF1 (serine and arginine rich splicing factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Srsf1 (serine and arginine-rich splicing factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf1 (serine and arginine rich splicing factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF1 (serine and arginine rich splicing factor 1)
Canis lupus familiaris (dog) : SRSF1 (serine and arginine rich splicing factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf1 (serine and arginine rich splicing factor 1)
Sus scrofa (pig) : SRSF1 (serine and arginine rich splicing factor 1)
Chlorocebus sabaeus (African green monkey) : SRSF1 (serine and arginine rich splicing factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01075,334,200 - 75,341,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1075,335,146 - 75,341,197 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01074,759,412 - 74,765,821 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,339,824 - 76,344,552 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1071,749,406 - 71,755,457 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Srsf1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587490
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.