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Gene: Srsf1 (serine and arginine rich splicing factor 1) Rattus norvegicus
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Symbol: Srsf1
Name: serine and arginine rich splicing factor 1
Description: Exhibits protein kinase B binding activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; liver regeneration; and positive regulation of RNA splicing. Localizes to the cytoplasm and nucleus. Predicted to colocalize with the exon-exon junction complex. Biomarker of hepatocellular carcinoma. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 6-propyl-2-thiouracil; all-trans-retinoic acid; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC689890; serine/arginine-rich splicing factor 1; Sfrs1; similar to splicing factor, arginine/serine-rich 1 (ASF/SF2); splicing factor, arginine/serine-rich 1; splicing factor, arginine/serine-rich 1B
Orthologs:
Homo sapiens (human) : SRSF1 (serine and arginine rich splicing factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Srsf1 (serine/arginine-rich splicing factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf1 (serine and arginine rich splicing factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF1 (serine and arginine rich splicing factor 1)
Canis lupus familiaris (dog) : SRSF1 (serine and arginine rich splicing factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf1 (serine and arginine rich splicing factor 1)
Sus scrofa (pig) : SRSF1 (serine and arginine rich splicing factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01075,334,200 - 75,341,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01074,759,412 - 74,765,821 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,339,824 - 76,344,552 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1071,749,406 - 71,755,457 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Srsf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587490
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.