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Gene: Timm50 (translocase of inner mitochondrial membrane 50) Rattus norvegicus
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Symbol: Timm50
Name: translocase of inner mitochondrial membrane 50
Description: Predicted to have interleukin-2 receptor binding activity; phosphoprotein phosphatase activity; and ribonucleoprotein complex binding activity. Predicted to be involved in several processes, including mitochondrial membrane organization; protein import into mitochondrial matrix; and release of cytochrome c from mitochondria. Predicted to localize to the TIM23 mitochondrial import inner membrane translocase complex and nuclear speck. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Orthologous to human TIMM50 (translocase of inner mitochondrial membrane 50); PARTICIPATES IN presequence pathway of mitochondrial protein import; INTERACTS WITH Brodifacoum; indole-3-methanol; troglitazone.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC685725; LOC687295; mitochondrial import inner membrane translocase subunit TIM50; similar to translocase of inner mitochondrial membrane 50 homolog; translocase of inner mitochondrial membrane 50 homolog
Orthologs:
Homo sapiens (human) : TIMM50 (translocase of inner mitochondrial membrane 50)  HGNC  Alliance
Mus musculus (house mouse) : Timm50 (translocase of inner mitochondrial membrane 50)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Timm50 (translocase of inner mitochondrial membrane 50)
Pan paniscus (bonobo/pygmy chimpanzee) : TIMM50 (translocase of inner mitochondrial membrane 50)
Canis lupus familiaris (dog) : TIMM50 (translocase of inner mitochondrial membrane 50)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Timm50 (translocase of inner mitochondrial membrane 50)
Sus scrofa (pig) : TIMM50 (translocase of inner mitochondrial membrane 50)
Chlorocebus sabaeus (African green monkey) : TIMM50 (translocase of inner mitochondrial membrane 50)
Heterocephalus glaber (naked mole-rat) : Timm50 (translocase of inner mitochondrial membrane 50)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0185,470,810 - 85,480,813 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,470,831 - 85,480,407 (+)Ensembl
Rnor_5.0186,684,416 - 86,691,956 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,399,403 - 83,400,789 (-)NCBIRGSC3.4rn4RGSC3.4
Celera177,973,840 - 77,981,578 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Timm50
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587684
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.